Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  PTEROIC ACID

PTEROIC ACID

Basic information Safety Related Supplier
PTEROIC ACID Basic information
PTEROIC ACID Chemical Properties
  • Melting point:>400℃
  • Boiling point:610.0±65.0 °C(Predicted)
  • Density 1.69
  • storage temp. 2-8°C
  • pka4.65±0.10(Predicted)
  • form neat
Safety Information
  • WGK Germany 3
MSDS
PTEROIC ACID Usage And Synthesis
  • UsesPteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.
  • Enzyme inhibitorThis metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.
  • Purification MethodsCrystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]
PTEROIC ACID(119-24-4)Related Product Information
PTEROIC ACIDSupplierMore
  • Company Name:Suzhou HuaJianruida Pharmaceutical Technology Co., Ltd. Gold
  • Tel:13913175631
  • Email:
  •  
  • Company Name:Changzhou Qiyu Biotechnology Co., Ltd. Gold
  • Tel:13961298435
  • Email:zzyqqq@163.com
  •  
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
  •  
  • Company Name:BeiJing Hwrk Chemicals Limted
  • Tel:18516978288 0757-86329057-
  • Email:sales.gd@hwrkchemical.com
  •  
  • Company Name:Energy Chemical
  • Tel:400-005-6266 021-58432009-
  • Email:sales8178@energy-chemical.com
  •