Description References
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Esculin

Description References
Esculin Structure
Esculin
  • CAS No.531-75-9
  • Chemical Name:Esculin
  • CBNumber:CB8245061
  • Molecular Formula:C15H16O9
  • Formula Weight:340.28
  • MOL File:531-75-9.mol
Esculin Property
  • Melting point: :203 °C
  • alpha  :-88 º (c=2,dioxane/water1:1)
  • Boiling point: :396.1°C (rough estimate)
  • Density  :0.791 g/mL at 20 °C
  • refractive index  :-79 ° (C=2.4, 50% Dioxane)
  • Flash point: :15 °C
  • storage temp.  :2-8°C
  • solubility  :methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
  • pka :7.00±0.20(Predicted)
  • form  :Liquid
  • color  :Clear
  • optical activity :[α]20/D 41±2°, c = 5% in pyridine
  • Water Solubility  :MODERATELY SOLUBLE
  • Merck  :3698
  • Stability: :Stable. Incompatible with strong oxidizing agents.
  • InChIKey :YRABYCJKUBFWQY-FHXAZYNBSA-N
  • CAS DataBase Reference :531-75-9(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :1Y1L18LQAF
  • NIST Chemistry Reference :7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
  • EPA Substance Registry System :Esculin (531-75-9)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Esculin Price More Price(7)
  • Brand: Sigma-Aldrich
  • Product number: E8250
  • Product name : Esculin hydrate
  • Purity: ≥98%
  • Packaging: 5g
  • Price: $42.8
  • Updated: 2018/11/20
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1.00842
  • Product name : Esculin
  • Purity: for microbiology
  • Packaging: 25 g
  • Price: $112
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: Y0001612
  • Product name : Esculin
  • Purity: European Pharmacopoeia (EP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 06212
  • Product name : Esculin hydrate
  • Purity: analytical standard
  • Packaging: 100mg
  • Price: $202
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: E8250
  • Product name : Esculin hydrate
  • Purity: ≥98%
  • Packaging: 100g
  • Price: $418
  • Updated: 2018/11/20
  • Buy: Buy

Esculin Chemical Properties,Usage,Production

  • Description Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.
  • References [1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
    [2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
    [3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
    [4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011
  • Chemical Properties White to nearly white
  • Uses esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.
  • Uses esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.
  • Definition ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.
Esculin Preparation Products And Raw materials
Raw materials
Preparation Products
Global(327)Suppliers
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531-75-9, EsculinRelated Search:
  • BICOLOIN
  • ESCULETIN-6-O-GLUCOSIDE
  • ESCULIN
  • ESCULETIN-6-GLUCOSIDE
  • ESCULOSIDE
  • Esculinsesquimonohydrate
  • 2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-
  • 6,7-DIHYDROXYCOUMARIN-6-O-GLUCOSIDE
  • 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-one
  • 6-(BETA-D-GLUCOPYRANOSYLOXY)-7-HYDROXY-2H-1-BEZOPYRAN-2-ONE
  • 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
  • 6,7-Dihydrocoumarin-6-glucoside
  • 6-β-Glucosido-7-hydrox
  • Aesculin;Bicolorin;6,7-Dihydrocoumarin-6-glucoside;6,7-Dihydroxycoumarin 6-glucoside;Enallachrome;Escosyl;Esculetin-6-β-D-glucopyranoside;Esculin;Esculinic acid;Esculoside;6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one;6-β-Glucosido-7-hydrox
  • Esculinic acid
  • ESCULIN, PLANT EXTRACT 10:1
  • AESCULIN (Esculin Sesquihydrate)
  • EsculinNLT98%
  • 7-hydroxycoumarin-6-yl beta-d-glucopyranoside
  • ESCULIN(ESCULETIN-6-GLUCOSIDE)(P)
  • 7-HYDROXY-6-O-GLUCOSYLCOUMARIN
  • 6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin
  • ESCULIN extrapure
  • 7-hydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one hydrate
  • AESCULETIN
  • AESCULETIN-6B-D-GLUCOPYRANOSIDE
  • AESCULETIN-6-BETA-D-GLUCOPYRANOSIDE
  • AESCULIN
  • POLYDROM
  • POLYCHROME
  • 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-on
  • Bicolorin
  • Crataegin
  • Enallachrome
  • Escosyl
  • Esculetin 6-beta-D-glucoside
  • Esculine
  • Polychrom
  • Vitamin C2
  • vitaminc2
  • 6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE
  • Esculin,Esculine
  • 6-(b-D-Glucopyranosyloxy)-7-hydroxycoumarin
  • Esculetin 6-b-D-glucoside
  • Esculin hydrate,97%
  • 6-glucoside hydrate
  • F. bangeana DC.p.e
  • 6-glucoside hydrat
  • 7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one
  • Esculin hydrate, 97% 10GR
  • Aesculin (Esculin)
  • Schillerstoff
  • 2H-1-Benzopyran-2-one,6-(b-D-glucopyranosyloxy)-7-hydroxy-
  • 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
  • 6,7-dihydroxychromen-2-one 6-β-D-glucoside
  • 6,7-dihydroxycoumarin 6-β-D-glucoside
  • 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy- 6-(hydroxymethyl)-2-tetrahydropyranyl]oxy}-2-chromenone
  • Esculetin 6-β-D-glucoside