Chemical Properties
Ethyl 4-phenylbutyrate has a sweet, fruity, plum-like odor and cooked plum–prune taste.
Uses
Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.
Definition
ChEBI: Ethyl 4-phenylbutanoate is a fatty acid ester.
Application
Ethyl-4-phenylbutanoate is probably used in flavors only. It imparts at a very low concentrations a certain amount of “natural” body and richness to many berries and other fruit flavours. The concentration used in such flavors is equivalent to about 0.06 to 1 ppm in the finished products.
Preparation
By esterification of ethanol with γ-phenylbutyric acid obtained by Grignard reaction from γ-bromopropylbenzene.
Synthesis Reference(s)
Journal of the American Chemical Society, 107, p. 1429, 1985
DOI: 10.1021/ja00291a063
