Description
(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It
can be used in the preparation of enantiopure carbocyclic
nucleosides, which act as a HIV protease inhibitor. It can also be
used as a chiral auxiliary in the enantioselective synthesis of (2R,
2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids.
Its end product includes asymmetric single isomeric drugs such as
antitumor, anesthetic and entipasmodic products.
Chemical Properties
white to light yellow crystal powde
Uses
(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.
Uses
intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan
References
http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.
