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Clozapine Structure

Clozapine

Chemical Properties

Melting point 182-185°C
Boiling point 482.71°C (rough estimate)
Density  1.1327 (rough estimate)
refractive index  1.6110 (estimate)
Flash point 9℃
storage temp.  2-8°C
solubility  ethanol: 1 mg/mL
pka 3.70, 7.60(at 25℃)
form  powder
color  pale yellow
Merck  14,2423
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference 5786-21-0(CAS DataBase Reference)
FDA UNII J60AR2IKIC
NCI Drug Dictionary clozapine
ATC code N05AH02
NIST Chemistry Reference Clozapine(5786-21-0)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H341-H361
Precautionary statements P201-P202-P264-P270-P280-P301+P310
Hazard Codes  Xn,Xi,T,F
Risk Statements  22-36/37/38-68-63-39/23/24/25-23/24/25-11
Safety Statements  26-36/37-45-16-7
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  HP1750000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29339900
Hazardous Substances Data 5786-21-0(Hazardous Substances Data)
Toxicity LD50 in mice, rats (mg/kg): 61, 58 i.v.; 199, 260 orally (Lindt)
NFPA 704:
3
2 0

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