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tert-Butyldimethylsilyl chloride

Introduction
tert-Butyldimethylsilyl chloride Structure
tert-Butyldimethylsilyl chloride
  • CAS No.18162-48-6
  • Chemical Name:tert-Butyldimethylsilyl chloride
  • CBNumber:CB3763003
  • Molecular Formula:C6H15ClSi
  • Formula Weight:150.72
  • MOL File:18162-48-6.mol
tert-Butyldimethylsilyl chloride Property
  • Melting point: :86-89 °C
  • Boiling point: :125 °C(lit.)
  • Density  :0.87 g/mL at 20 °C(lit.)
  • refractive index  :n20/D 1.46
  • Flash point: :73 °F
  • storage temp.  :Store at 5°C
  • form  :Liquid
  • color  :Clear colorless
  • Specific Gravity :1.225
  • Water Solubility  :Soluble in chloroform and ethyl acetate. Insoluble in water.
  • Hydrolytic Sensitivity :8: reacts rapidly with moisture, water, protic solvents
  • Hydrolytic Sensitivity :7: reacts slowly with moisture/water
  • Sensitive  :Moisture Sensitive
  • BRN  :505999
  • InChIKey :BCNZYOJHNLTNEZ-UHFFFAOYSA-N
  • CAS DataBase Reference :18162-48-6(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :550OPF5Z9F
  • NCI Dictionary of Cancer Terms :BDCS
  • NIST Chemistry Reference :Silane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
  • EPA Substance Registry System :Silane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H304-H314-H336-H361d-H373-H302-H335-H351-H226-H228-H318-H361
  • Precautionary statements P309-P240-P241-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P210-P261-P280-P301+P310-P305+P351+P338-P310-P260-P370+P378-P403+P235
tert-Butyldimethylsilyl chloride Price More Price(24)
  • Brand: Sigma-Aldrich
  • Product number: 06735
  • Product name : tert-Butyldimethylsilyl chloride
  • Purity: for GC derivatization, ≥99.0% (GC)
  • Packaging: 10g
  • Price: $91.5
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 06735
  • Product name : tert-Butyldimethylsilyl chloride
  • Purity: for GC derivatization, ≥99.0% (GC)
  • Packaging: 10x1g
  • Price: $106
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: B0995
  • Product name : tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]
  • Purity: >98.0%(GC)
  • Packaging: 5g
  • Price: $24
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: B0995
  • Product name : tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]
  • Purity: >98.0%(GC)
  • Packaging: 25g
  • Price: $79
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: A13064
  • Product name : tert-Butyldimethylchlorosilane
  • Purity: 97%
  • Packaging: 25g
  • Price: $86
  • Updated: 2020/06/24
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tert-Butyldimethylsilyl chloride Chemical Properties,Usage,Production

  • Introduction Triethylchlorosilane is a clear, colourless to yellowish, pungent smelling, caustic and flammable liquid. It can be dissolved in non-protonating solvents without decomposition.
    It may be used as silylating agent for dervatization of primary and secondary alcohols etc.. Also it may be used to protect allylic esters as silylketene acetal which is ore stable but less volatile derivates than trimethylchlorosilane.
  • Chemical Properties White solid
  • Uses Used to protect alcohols during organic synthesis.
  • Definition ChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry ap lications.
  • Hazard Moderately toxic.
  • Purification Methods Fractionally distil it at atmospheric pressure. [Sommer & Tyler J Am Chem Soc 76 1030 1954, Corey & Venkateswarlu J Am Chem Soc 94 6190 1972, Beilstein 4 IV 4076.]
tert-Butyldimethylsilyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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