Chemical Properties
Colorless to yellow liquid
Uses
4-Chloromethyl-3,5-dimethylisoxazole has been used in the preparation of:
- 4(3-oxoalkyl)isoxazole
- (E)-3,5-dimethyl-4-(2-(thiophene-3-yl)vinyl)isoxazole
Application
4-(Chloromethyl)-3,5-dimethylisoxazole is an annulation reagent used for the construction of cyclohexenones in the syntheses of steroids, terpenes, and alkaloids.
General Description
4-Chloromethyl-3,5-dimethylisoxazole participates in asymmetric isoxazole annulation reaction.
storage
Handling, Storage, and Precautions of 4-(Chloromethyl)-3,5-dimethylisoxazole: light-sensitive lachrymator; refrigerate; handle and store under
nitrogen.