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Flufenamic acid

Flufenamic acid Structure
Flufenamic acid
  • CAS No.530-78-9
  • Chemical Name:Flufenamic acid
  • CBNumber:CB7118092
  • Molecular Formula:C14H10F3NO2
  • Formula Weight:281.23
  • MOL File:530-78-9.mol
Flufenamic acid Property
  • Melting point: :132-135 °C(lit.)
  • Boiling point: :373.9±42.0 °C(Predicted)
  • Density  :1.3380 (estimate)
  • storage temp.  :Keep in dark place,Inert atmosphere,Room temperature
  • pka :pKa 3.9 (Uncertain);3.85 (Uncertain)
  • form  :Crystalline Powder or Chunks
  • color  :Off-white to gray-green
  • Water Solubility  :0.0265 g/L (37 ºC)
  • Merck  :14,4132
  • BRN  :1996069
  • CAS DataBase Reference :530-78-9(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :60GCX7Y6BH
  • NIST Chemistry Reference :Flufenamic acid(530-78-9)
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22-36/38
  • Safety Statements  :26
  • RIDADR  :UN 2811 6.1/PG 3
  • WGK Germany  :3
  • RTECS  :CB4375000
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • HS Code  :29224999
  • Toxicity :LD50 in mice: 715 mg/kg orally (Zoni)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H302-H335-H301-H315-H319
  • Precautionary statements P261-P280a-P304+P340-P405-P501a-P301+P310-P305+P351+P338
Flufenamic acid Price More Price(11)
  • Brand: Sigma-Aldrich
  • Product number: F9005
  • Product name : Flufenamic acid
  • Purity: analytical standard, for drug analysis
  • Packaging: 10g
  • Price: $22.6
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: F9005
  • Product name : Flufenamic acid
  • Purity: analytical standard, for drug analysis
  • Packaging: 50g
  • Price: $76.5
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: T2354
  • Product name : N-(3-Trifluoromethylphenyl)anthranilic Acid
  • Purity: >98.0%(HPLC)(T)
  • Packaging: 25g
  • Price: $43
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: T2354
  • Product name : N-(3-Trifluoromethylphenyl)anthranilic Acid
  • Purity: >98.0%(HPLC)(T)
  • Packaging: 500g
  • Price: $350
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: B23583
  • Product name : Flufenamic acid, 97%
  • Purity: 
  • Packaging: 10g
  • Price: $20
  • Updated: 2020/06/24
  • Buy: Buy

Flufenamic acid Chemical Properties,Usage,Production

  • Chemical Properties Pale-Yellow Solid
  • Originator Flufenamic acid,AroKor Holdings Inc.
  • Uses Flufenamic acid is used for moderate pain and dysmenorrhea, but it should not be used for more than 1 week due to the possibility of nephrotoxicity, gastrointestinal toxicity, and anemia. It is frequently used in combination with the anticoagulant warfarin, the effect of which is strengthened when combined with flufenamic acid.
  • Uses Anti-inflammatory; analgesic
  • Manufacturing Process A mixture 31.3 g of o-chlorobenzoic acid, 32.2 g of trifluoromethyl-maminobenzene, 3 g of copper powder, 13.8 g of waterless potassium carbonate and 100 ml amyl alcohol was refluxed for 4 hours. To the cooled mixture was added 25 ml of 10 N solution NaOH and the mixture was concentrated and filtrated. Addition to the filtrate hydrochloric acid and water give a sediment of 2-((3-trifluromethyl)phenyl)aminobenzoic acid. After recrystallization from hexane 2-((3-trifluromethyl)phenyl)aminobenzoic acid have melting point 134-136°C.
  • brand name Arlef (Parke-Davis).
  • Therapeutic Function Antiinflammatory, Antirheumatic
  • Chemical Synthesis Flufenamic acid, N-(α,α,α-trifluoro-m-tolyl)anthranylic acid (3.2.18), is synthesized by the reaction of 2-chlorobenzoic acid with 3-trifluoromethylaniline in the presence of potassium carbonate and copper filings [78,79].

Flufenamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global(201)Suppliers
  • Supplier:
    Henan Tianfu Chemical Co.,Ltd.
  • Tel:0371-55170693
  • Fax:0371-55170693
  • Email:info@tianfuchem.com
  • Country:CHINA
  • ProdList:22607
  • Advantage:55
  • Supplier:
    Xiamen AmoyChem Co., Ltd
  • Tel:+86 592-605 1114
  • Fax:
  • Email:sales@amoychem.com
  • Country:CHINA
  • ProdList:6369
  • Advantage:58
  • Supplier:
    career henan chemical co
  • Tel:13203830695 0086-371-86658258
  • Fax:0086-371-86658258
  • Email:factory@coreychem.com
  • Country:CHINA
  • ProdList:29865
  • Advantage:58
530-78-9, Flufenamic acidRelated Search:
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  • Flufenamic acid Solution, 100ppm
  • N-(3-[Trifluoromethyl]phenyl)anthranilic acid, N-(α,α,α-Trifluoro-m-tolyl)anthranilic acid
  • 2-((3-(trifluoromethyl)phenyl)amino)-benzoicaci
  • 2-((3-Trifluromethyl)phenyl)aminobenzoic acid
  • Achless
  • Acido flufenamico
  • acidoflufenamico
  • Ansatin
  • ANT-1
  • Anthranilic acid, N-(alpha,alpha,alpha-trifluoro-m-tolyl)-
  • Flufenamic acid, 97%, an anti-inflammatory agent
  • Flufenamic acid (FFA)
  • Etofenamate EP Impurity A
  • Arlef
  • Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-
  • C.I. 440
  • CI 440
  • TIMTEC-BB SBB001140
  • N-(A,A,A-TRIFLUORO-M-TOLYL)ANTHRANILIC ACID
  • N-(ALPHA,ALPHA,ALPHA-TRIFLUOROMETHYL-M-TOLYL)ANTHRANILIC ACID
  • N-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)ANTHRANILIC ACID
  • N-(3-TRIFLUOROMETHYLPHENYL)ANTHRANILIC ACID
  • Paraflu
  • Parlef
  • Parlif
  • Plostene
  • Reumajust A