Chemical Properties
clear colorless to light yellow liquid or low
Uses
3,5-Dichlorobenzoyl chloride has been used in the preparation of:
- N-(1,1-dimethylpropynyl)-3,5-dichlorobenzamide, herbicide
- (3,5-dichlorophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone
Uses
3,5-Dichlorobenzoyl chloride is a useful intermediate for organic synthesis and other pharmaceutical processes.
Flammability and Explosibility
Non flammable
Synthesis
3,5-Dichlorobenzoyl chloride is obtained by reacting by aryl carboxylic acid with DMF.Dissolve aryl carboxylic acid (10.0 mmol) in 50 mL DCM with drops of DMF to a 100 mL roundbottomed flask. Cool the mixture to 0°C. Add oxalyl chloride (20.0 mmol, 2.0 equivalents) dropwise to the reaction mixture. Allow the reaction mixture to react for another 4 hours. Concentrate the solvent in vacuo. Use the remaining residue directly.
Fig The synthetic method of 3,5-Dichlorobenzoyl chloride
