Uses
Therapeutic use of Flupirtine was discontinued due to drug induced liver injury (DILI). Since the mechanism of action is not related to its adverse effects, it is important to focus on chemical modifications.
Definition
ChEBI: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester is an aminopyridine.
Clinical Use
Flupirtine maleate is an
analgesic with an unknown mode of action. It is
used in single doses of 100 mg orally and 150
mg rectally for the treatment of different pain
conditions.