Bis(tri-tert-butylphosphine)palladium(0)

Reaction

1. Introduced as an easier to handle Pd/P(t-Bu)3-based catalyst for the Negishi cross-coupling of aryl/vinyl chlorides.
2. A versatile catalyst for the cross-coupling of aryl and vinyl chlorides.
3. Catalyst for the amination of aryl chlorides and bromides using aqueous hydroxide bases.
4. Useful catalyst for the cross-coupling of heteroaromatic carboxylic acids.
5. Pd-catalyzed Newnan-Kwart rearrangement of O-aryl thiocarbamates.
6. Cross-coupling of silanolates and halides.
7. Elimination/isomerization of enol triflates derived from β-ketoesters.

 

Chemical Properties

Off white crystalline solid

Uses

Catalyst for Suzuki coupling on a multisubstituted sp 3 -carbon (eq. 1) Catalyst for Stille coupling reaction of aryl chlorides 2 (eq. 2) Catalyst for Negishi coupling reaction 3 (eq. 3) Catalyst for Heck coupling to form tetrasubstituted olefins 4 (eq. 4) Catalyst for Buchwald-Hartwig amination of aryl halide 5 (eq. 5) Catalyst for carbonylation of aryl halides with carbamoylsilanes 6 (eq. 6) t -Bu 3 P) 2 catalyst.

Uses

Bis(tri-tert-butylphosphine)palladium(0) is used in Coupling reactions, Heck couplings. It acts as a palladium catalyst for reductive carbonylation.

General Description

This product has been enhanced for catalytic efficiency.

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst