Chemical Properties
Yellow crystalline powder
Uses
2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone. It was also used in synthesis of 5,6-dihydroxyflavone.
Uses
2''-Hydroxy-6''-methoxyacetophenone is useful in the synthesis of an aminopyrazole compound which is used to treat cancer and inhibits Chk1. 2''-Hydroxy-6''-methoxyacetophenone is also used to prepare 5,?4''-?disubstituted flavones, predicted androgen receptor antagonists and naphthopyrazolyl carbothioamides which are anticancer agents.
Preparation
Preparation by reaction of methyl iodide on 2,6-dihydroxyacetophenone with potassium carbonate in boiling acetone (56%).
Definition
ChEBI: 2'-Hydroxy-6'-methoxyacetophenone is an aromatic ketone.
General Description
An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported.
