Chemical Properties
WHITE TO OFF-WHITE FINE NEEDLE-LIKE CRYST. POWDER
Uses
Nicotinic hydrazide was used in hydrazone library formation. It was used to study the oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase.
Uses
An Impurity of Isoniazid (I821450), potent antitubercular agent against M. tuberculosis.
Biochem/physiol Actions
Nicotinic hydrazide is an inhibitor of peroxidase enzyme. It forms solid metal complexes having strong biological activity.
Purification Methods
Crystallise it from aqueous EtOH or *benzene. [Beilstein 22 III/IV 439, 22/2 V 121.]
