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Nicotinic acid Structure

Nicotinic acid

Chemical Properties

Melting point 236-239 °C(lit.)
Boiling point 260C
Density  1.473
refractive index  1.5423 (estimate)
Flash point 193°C
storage temp.  2-8°C
solubility  18g/l
form  Powder
pka 4.85(at 25℃)
color  White to off-white
PH 2.7 (18g/l, H2O, 20℃)
Odor odorless to sl. odor, sour taste
Water Solubility  1-5 g/100 mL at 17 ºC
Merck  14,6525
BRN  109591
BCS Class 3
Stability Stable. Incompatible with strong oxidizing agents. May be light sensitive.
LogP 0.360
FDA 21 CFR 184.1530; 582.5530; 104.20; 107.10; 136.115; 137.165; 137.185
Substances Added to Food (formerly EAFUS) NIACIN
SCOGS (Select Committee on GRAS Substances) Niacin (nicotinic acid)
CAS DataBase Reference 59-67-6(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms niacin; nicotinic acid
NCI Drug Dictionary niacin
ATC code C04AC01,C10AD02,C10AD52
NIST Chemistry Reference Niacin(59-67-6)
EPA Substance Registry System Nicotinic acid (59-67-6)


Signal wordWarning
Hazard statements H319
Precautionary statements P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-36-39/23/24/25-23/24/25-11
Safety Statements  26-36-24/25-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
RTECS  QT0525000
Autoignition Temperature >365 °C Dust
HS Code  29362990
Hazardous Substances Data 59-67-6(Hazardous Substances Data)
Toxicity LD50 s.c. in rats: 5 g/kg (Brazda, Coulson)
NFPA 704:
2 0

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