DEXTRANASE

Uses

Dextranase from Penicillium sp has been used:

• in the digestion of exopolysaccharides from P. aeruginosa biofilms and dextran polymers
• as a component of trypticase soy broth (TSYPS) for Streptococcus mutans culture
• in microgel degradation

Uses

Dextranase from Chaetomium erraticum has been used:

• in microcarrier dissolution to produce multicellular 3D spheroids for drug discovery
• in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolates
• in a study to investigate the immobilization of dextranase
• to investigate the optimization of process conditions for enzymatic modification of alternan

Uses

Dextranase can be used in preparation of dextran for clinical use.

General Description

Dextranase from fungi belong to the glycoside hydrolase families (GH) 49. Dextranase from Penicillium sp. are stable at varying temperature and pH.

Biochem/physiol Actions

An endodextranase that hydrolyzes -(1,6)-glucosidic linkages in dextran. Dextrans are undesirable compounds synthesized from sucrose by microbial contaminants during sugar production that increase viscosity of the flow and decrease industrial recovery. Dextranase has been used for hydrolyzing dextran at sugar mills in order to improve efficiency of sugar production.