ChemicalBook > CAS DataBase List > MINAPRINE DIHYDROCHLORIDE

MINAPRINE DIHYDROCHLORIDE

MINAPRINE DIHYDROCHLORIDE Structure
MINAPRINE DIHYDROCHLORIDE
  • CAS No.25905-77-5
  • Chemical Name:MINAPRINE DIHYDROCHLORIDE
  • CBNumber:CB4686336
  • Molecular Formula:C17H22N4O
  • Formula Weight:298.38
  • MOL File:25905-77-5.mol
MINAPRINE DIHYDROCHLORIDE Property
  • Melting point: :122°
  • Boiling point: :531.2±50.0 °C(Predicted)
  • Density  :1.156±0.06 g/cm3(Predicted)
  • pka :6.80±0.10(Predicted)
  • form  :neat
  • ATC code :N06AX07
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22
  • Safety Statements  :36
  • WGK Germany  :3
  • RTECS  :QE3477830
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements
MINAPRINE DIHYDROCHLORIDE Price More Price(1)
  • Brand: Sigma-Aldrich
  • Product number: M3157
  • Product name : Minaprine dihydrochloride
  • Purity: analytical standard
  • Packaging: 1g
  • Price: $54
  • Updated: 2021/03/22
  • Buy: Buy

MINAPRINE DIHYDROCHLORIDE Chemical Properties,Usage,Production

  • Originator Cantor,Clin Midy,France,1979
  • Uses muscle relaxant (skeletal)
  • Manufacturing Process (a) Preparation of the free base: A mixture comprising 0.1 mol (20.4 g) of 3-chloro-4-methyl-6-phenylpyridazine and 0.2 mol (26.2 g) of N-(2-aminoethyl)-morpholine in 100 ml of n-butanol, with a pinch of copper powder, was heatedunder reflux for 12 hours. At the end of this time, the hot solution was pouredinto 200 ml of cold water. The resulting mixture was filtered through asintered glass filter and the precipitate washed with ether. The filtrate and theether washings were placed in a separating funnel and extracted with two 150ml portions of ether. The ethereal layer was then extracted with about 250 mlof N sulfuric acid.
    The acid solution was made alkaline with a 10% aqueous solution of sodiumcarbonate, and left to crystallize overnight.
    The solution was filtered, yielding the colorless needles which wererecrystallized from isopropanol. The yield was 15 g (53%).
    (b) Preparation of the hydrochloride: The base was dissolved in the smallestamount possible of anhydrous acetone. Double that volume of anhydrousether was added, and a stream of hydrogen chloride gas was passed throughthe solution. The hydrochloride salt obtained was recrystallized from absolutealcohol. The yield after recrystallization was 17 g (90%).
  • brand name Cantor (Sanofi).
  • Therapeutic Function Antidepressant
MINAPRINE DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
MINAPRINE DIHYDROCHLORIDE Suppliers
Global(45)Suppliers
  • Supplier:
    Hangzhou FandaChem Co.,Ltd.
  • Tel:008615858145714
  • Fax:+86-571-56059825
  • Email:fandachem@gmail.com
  • Country:CHINA
  • ProdList:8910
  • Advantage:55
  • Supplier:
    Target Molecule Corp
  • Tel:18019718960 781-999-5354
  • Fax:
  • Email:marketing@targetmol.com
  • Country:United States
  • ProdList:19232
  • Advantage:58
  • Supplier:
    Alfa Chemistry
  • Tel:+1-516-662-5404
  • Fax:1-516-927-0118
  • Email:inquiry@alfa-chemistry.com
  • Country:United States
  • ProdList:10563
  • Advantage:58
  • Supplier: LGM Pharma
  • Tel:1-(800)-881-8210
  • Fax:615-250-9817
  • Email:inquiries@lgmpharma.com
  • Country:United States
  • ProdList:1938
  • Advantage:70
  • Supplier: BOC Sciences
  • Tel:16314854226
  • Fax:
  • Email:info@bocsci.com
  • Country:United States
  • ProdList:21113
  • Advantage:65
  • Supplier: Haoyuan Chemexpress Co., Ltd.
  • Tel:86-21-58998985
  • Fax:(86) 21-58955996
  • Email:apisales@chemexpress.com.cn
  • Country:China
  • ProdList:7557
  • Advantage:61
  • Supplier: MedChemexpress LLC
  • Tel:609-228-6898
  • Fax:609-228-5909
  • Email:sales@medchemexpress.com
  • Country:United States
  • ProdList:4787
  • Advantage:58
25905-77-5, MINAPRINE DIHYDROCHLORIDERelated Search:
  • n-(4-methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamin
  • n-(4-methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine
  • minaprin
  • Minaprin diHCl
  • N-(4-Methyl-6-phenylpyridazin-3-yl)-4-morpholineethanamine
  • TS-370
  • N-[4-METHYL-6-PHENYL-3-PYRIDAZINYL]-4-MORPHOLINEETHANAMINE DIHYDROCHLORIDE
  • MINAPRIN DIHYDROCHLORIDE
  • MINAPRINE DIHYDROCHLORIDE
  • MINAPRINE HYDROCHLORIDE
  • Minaprine 2HCl
  • minaprine
  • Cantor
  • Minaprina
  • Minaprinum
  • 4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-
  • 25905-77-5
  • C17H22N4O
  • C17H22N4O2HCl
  • METI - MZ
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • Active Pharmaceutical Ingredients
  • NAMENDA