Application
In asymmetric synthesis, the synthesis of chiral catalysts or chiral auxiliaries is crucial. Chiral amino alcohols are widely used as ligands or catalysts for catalyzing asymmetric synthetic reactions and are also important precursors for the synthesis of many chiral drugs, natural products, and chemical and biological functional materials. (S)-2-amino-1,1-diphenyl-1-propanol belongs to the optically active β-amino alcohols. It can be used for asymmetric reduction of pre-chiral ketones, asymmetric catalytic epoxidation reactions, and asymmetric catalytic alkylation reactions of carbonyl compounds. (S)-2-amino-1,1-diphenyl-1-propanol has also been reported as an intermediate in the synthesis of chiral complexes in asymmetric cyclopropanation reactions.
