Chemical Properties
colourless or slightly brown liquid
Uses
C
2 symmetric chiral diol with versatile applications as a chiral auxiliary, building block, and chiral ligand. Cyclocondenses with ketones for
13C
NMR determination of optical purity.
Uses
(2R,3R)-(-)-2,3-Butanediol is used as a chiral auxiliary, chiral ligand and building block. Cyclocondenses with ketones for (13)C NMR determination of optical purity. It is used in the resolution of carbonyl compounds in gas chromatography.
Definition
ChEBI: The (R,R) diastereoisomer of butane-2,3-diol.
General Description
(2
R,3
R)-(-)-2,3-Butanediol is a key building block in pharmaceutical industry.
Flammability and Explosibility
Not classified
Purification Methods
Purify it by fractional distillation. The bis-(4-nitrobenzoate) has m 141-142o and [] (-) or (+) 52o (c 4 CHCl3). [Ghirardelli & Lucas J Am Chem Soc 79 734 1957, Rubin et al. J Am Chem Soc 74 425 1952, Neish Can J Res 27 6 1949, Neish & Ledingham Can J Res 27 694 1949, Beilstein 1 IV 2524-2525.]
