Chemical Properties
Crystal structure of 3-bromoisonicotinic acid (C6H4BrNO2): triclinic, P
ˉ1 (no. 2), a = 7.2512(6) ?,
b = 7.3916(6) ?, c = 7.4920(7) ?, α = 65.065(4)°, β =
68.858(4)°, γ = 64.919(4)°, V = 321.60(5) ?3
, Z = 2,
Rgt(F) = 0.0369, wRref(F
2
) = 0.1017, T = 150(2) K.
Uses
3-Bromoisonicotinic acid, as the most important intermediate in isonicotinic acid derivatives, is mainly used in the manufacture of anti-tuberculosis drugs, but also in the synthesis of amides, hydrazides, esters and other derivatives.
