Description
1,2-Dipalmitoyl-
sn-glycero-3-PG (1,2-DPPG) is a phospholipid containing the long-chain (16:0) palmitic acid inserted at the
sn-1 and
sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
Uses
1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) forms lipid bilayers. In the high temperature phase, the conformation of the chains is liquid-like. In the low temperature phases, the chains are stiff and parallel and they interdigitate.
References
[1] CANAY EGE Ka Y C L. Insertion of Alzheimer’s A beta 40 peptide into lipid monolayers.[J]. Biophysical journal, 2004, 87 3: 1732-1740. DOI:
10.1529/biophysj.104.043265[2] HEIDI M. MANSOUR George Z. The relationship between water vapor absorption and desorption by phospholipids and bilayer phase transitions[J]. Journal of pharmaceutical sciences, 2007, 96 2: Pages 377-396. DOI:
10.1002/jps.20810