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1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine

1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Structure
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine
  • CAS No.4004-05-1
  • Chemical Name:1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine
  • CBNumber:CB2477530
  • Molecular Formula:C41H78NO8P
  • Formula Weight:744.05
  • MOL File:4004-05-1.mol
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Property
  • Melting point: :200°C(lit.)
  • Boiling point: :759.2±70.0 °C(Predicted)
  • Density  :1.008±0.06 g/cm3(Predicted)
  • storage temp.  :-20°C
  • form  :lyophilized powder
  • pka :1.17±0.50(Predicted)
  • BRN  :1718431
  • FDA UNII :JNP6V6AI0U
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H302-H315-H319-H331-H336-H351-H361d-H372
  • Precautionary statements P261-P281-P305+P351+P338-P311
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Price More Price(29)
  • Brand: Sigma-Aldrich
  • Product number: 42490
  • Product name : 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
  • Purity: ≥99.0% (10 mg phospholipid per ml CHCl3, TLC)
  • Packaging: 2.5ml
  • Price: $72.9
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 42490
  • Product name : 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
  • Purity: ≥99.0% (10 mg phospholipid per ml CHCl3, TLC)
  • Packaging: 10ml
  • Price: $262
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: D4251
  • Product name : 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
  • Purity: >98.0%(T)
  • Packaging: 250mg
  • Price: $194
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 15091
  • Product name : 1,2-Dioleoyl-sn-glycero-3-PE
  • Purity: ≥98%
  • Packaging: 100mg
  • Price: $65
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 15091
  • Product name : 1,2-Dioleoyl-sn-glycero-3-PE
  • Purity: ≥98%
  • Packaging: 250mg
  • Price: $98
  • Updated: 2021/12/16
  • Buy: Buy

1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Chemical Properties,Usage,Production

  • Description 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar vesicles (GUVs).
    Phosphatidylethanolamine (PE) is formed primarily in the reaction of CDP-ethanolamine and diacylglycerol. PE is one of the major components of cell membranes in bacteria and in nervous system.
  • Chemical Properties Yellowish wax
  • Uses 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents.
  • Uses 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
  • Application 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
  • Definition ChEBI: Dioleoyl phosphatidylethanolamine is a phosphatidylethanolamine in which the phosphatidyl acyl groups are both oleoyl.
  • Biological Activity DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).
  • Biochem/physiol Actions DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Preparation Products And Raw materials
Raw materials
Preparation Products
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4004-05-1, 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamineRelated Search:
  • 3-SN-PHOSPHATIDYLETHANOLAMINE, 1,2-DIDEOYL
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
  • 1,2-DI([CIS]-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
  • 18:1 PE
  • L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL
  • L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL (C18:1,[CIS]-9)
  • L-BETA,GAMMA-DIOLEOYL-ALPHA-CEPHALIN
  • DIOLEOYL PHOSPHATIDYL ETHANOLAMINE
  • DOPE
  • 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 98+%
  • L-A-phosphatidylethanolamine dioleoyl
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-ETHA-N OLAMINE, 10 MG/ML
  • COATSOME ME-8181 (DOPE)
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, >99%
  • 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, DOPE
  • L-α-Phosphatidylethanolamine, dioleoyl
  • 3-sn-Phosphatidylethanolamine, 1,2-dideoyl, L-β,γ-Dioleoyl-α-cephalin, DOPE
  • (+)-1-O,2-O-Dioleoyl-L-glycerol 3-(phosphoric acid 2-aminoethyl) ester
  • 1,2-Dioleoyl-3-sn-phosphatidylethanolamine
  • O-(1-O,2-O-Dioleoyl-L-glycero-3-phospho)-2-aminoethanol
  • Phosphoric acid hydrogen (2-aminoethyl)[(2R)-2,3-bis(oleoyloxy)propyl] ester
  • Dioleoyl phosphoethanolamine
  • (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine
  • L-β,γ-Dioleoyl-α-cephalin
  • PE(18:1(9Z)/18:1(9Z))
  • 1,2-Dioleoyl-sn-glycero-3-PE
  • L-A-PHOSPHATIDYLETHANOLAMINE, DIOLEO
  • 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine≥ 98% (HPTLC)
  • 2-Aminoethyl (R)-2,3-bis(oleoyloxy)propyl hydrogen phosphate
  • 1,2-Dioleoyl-<i>sn</i>-glycero-3-phosphoethanolamine
  • 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
  • 9-Octadecenoic acid (9Z)-, 1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
  • 18:1 (Delta9-Cis) PE (DOPE)
  • dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE)
  • 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLETHANOLAMINE
  • (Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
  • 4004-05-1
  • 4004/5/1
  • BioChemical
  • Biochemicals and Reagents
  • Glycerophosphonoethanolamines
  • Glycerides
  • Cloning and Expression
  • Lipids
  • Molecular Biology
  • Phosphoglycerides
  • Transfection &amp; Transformation