Appearance
White to Almost white powder to crystal
Description
Dilauryl thiodipropionate (DLTDP) is a part synthetic, part plant-derived ester blend made from the fatty alcohol lauryl alcohol and the antioxidant thiodipropionic acid. Not surprisingly, it has antioxidant benefits on the skin and, according to older research from Avon, may play a role in fading the appearance of discolourations. It also works in cosmetics as a sequestering agent, which helps keep ingredients in a formula from having unwanted interactions. As such, it also helps stabilize cosmetics. DLTDP is a secondary artificial antioxidant widely used to extend the shelf life of products in the food, cosmetic, and polymer industries. Furthermore, some studies on asphalt antioxidants warned about the softening effect of DLTDP on asphalt binders, even after ageing. DLTDP has been declared by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) for use in food and cosmetics, which implies its safe use when used as intended and under specific limitations (based mainly on fat content)[1].
Chemical Properties
White flocculent crystalline solid. Insoluble in water, soluble in organic solvents such as acetone, carbon tetrachloride, benzene, petroleum ether, etc. Solubility in various solvents at 20°C (g/100g solvent) is: acetone 20; carbon tetrachloride 100; benzene 133; petroleum ether 40.
Uses
Didodecyl 3,3''-Thiodipropionate is an antioxidant used as a modifier to stabilize acrylonitrile-butadiene-styrene (ABS) graft copolymers due to a strong synergistic effect.
Uses
Dilauryl Thiodipropionate (DLTDP) is an antioxidant that exists as white crystalline flakes of sweetish ester-like odor. It is insoluble in water but soluble in inorganic solvents. It is used in fats and oils to prevent rancidity. It is used in food when the total antioxidant content is not over 0.02% of the fat or oil content.
Uses
Didodecyl 3,3'-Thiodipropionate (dilauryl thiodipropionate) is an antioxidant used as a modifier to stabilize acrylonitrile-butadiene-styrene (ABS) graft copolymers due to a strong synergistic effect. This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Definition
ChEBI: Didodecyl thiobispropanoate is a dicarboxylic acid.
Flammability and Explosibility
Non flammable
Safety Profile
An eye irritant. When
heated to decomposition it emits toxic
fumes of SOx. Thiodipropionic Acid and Dilauryl Thiodipropionate are also on the list of substances that are Generally Recognized As Safe (GRAS ) as chemical preservatives for use in foods.
Toxicology
According to the classification scheme of Hodge and Sterner, thiodipropionic acid (TDPA) and Dilauryl thiodipropionate (DLTDP) were slightly toxic when administered to mice and rats by the oral route. TDPA, when administered intraperitoneally, was moderately toxic to rats, while DLTDP was slightly toxic. TDPA was moderately toxic when administered intravenously to mice. TDPA and DLTDP were considered relatively nontoxic in subchronic oral toxicity studies with rats. No specific treatment-related effects were noted when TDPA was administered in the drinking water to guinea pigs for 4 months. No irritation was produced by a makeup foundation containing 0.05% DLTDP when tested at 0.0025% on intact and abraded skin of New Zealand white rabbits. Neither TDPA nor DLTDP produced signs of irritation when applied to the shaved skin of rabbits for 24 hours. In a guinea pig maximisation test, a makeup foundation containing 0.05% DLTDP was not a sensitizer. TDPA was tested for sensitization potential in guinea pigs, and though there were signs of local irritation at the injection sites, the TDPA was not considered a sensitizer. DLTDP was not phototoxic to New Zealand white rabbits at a concentration of 0.05% in a makeup foundation. No signs of irritation were observed when a solution containing TDPA was placed into the conjunctival sacs of rabbits. TDPA was neither a teratogen nor a reproductive toxicant when administered orally to mice, rats, hamsters, or rabbits during gestation.
References
[1] I. Camargo. “Dilauryl thiodipropionate as a regeneration agent for reclaimed asphalts.” Construction and Building Materials (2023).
