1,9alpha,11alpha,15S-tetrahydroxy-prost-13e-ene

Description

Prostaglandin F_1α (PGF_1α) alcohol is an analog of PGF_1α with a primary alcohol replacing the C-1 carboxyl group. There are no published reports on the biological activity of this compound; however, the corresponding PGE₁ analog is a relatively selective EP₃ and EP₄ receptor ligand.¹

Uses

Prostaglandin F1α alcohol is an analog of PGF1α[1].

Definition

ChEBI: Prostaglandin F1alpha alcohol is a member of the class of prostaglandins Falpha that is prostaglandin F1alpha in which the carboxy group has been reduced to the corresponding primary alcohol. It is a tetrol, a prostaglandins Falpha, a secondary allylic alcohol and a primary alcohol. It is functionally related to a prostaglandin F1alpha.

References

1. Kiriyama, M., Ushikubi, F., Kobayashi, T., et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br. J. Pharmacol. 122(2),217-224(1997).