Description
Prostaglandin F
1α (PGF
1α) alcohol is an analog of PGF
1α with a primary alcohol replacing the C-
1 carboxyl group. There are no published reports on the biological activity of this compound; however, the corresponding PGE
1 analog is a relatively selective EP
3 and EP
4 receptor ligand.
1
Definition
ChEBI: Prostaglandin F1alpha alcohol is a member of the class of prostaglandins Falpha that is prostaglandin F1alpha in which the carboxy group has been reduced to the corresponding primary alcohol. It is a tetrol, a prostaglandins Falpha, a secondary allylic alcohol and a primary alcohol. It is functionally related to a prostaglandin F1alpha.
References
1. Kiriyama, M., Ushikubi, F., Kobayashi, T., et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br. J. Pharmacol. 122(2),217-224(1997).
