Chemical Properties
clear dark brown liquid
Uses
3-(Methylthio)aniline was used in the synthesis of phenyl azobenzene sulfonamide derivatives.
Uses
Pharmaceutical intermediate.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors ofNO
x and SO
x.
Purification Methods
Purify the aniline by fractional distillation in an inert atmostphere. It has UV max at 226 and 300nm. [Bordwell & Cooper J Am Chem Soc 74 10581952.] The N-acetyl derivative has m 78-78.5o (from aqueous EtOH). The hydrochloride has m 260-261o (aqueous EtOH/HCl) or m 225-227o (EtOH/Et2O). [Beilstein 13 H 533, 13 III 1221, 13 IV 1289.]
