Description
Kirromycin is an antibiotic originally isolated from
Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of
B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in
E. coli.
Uses
Kirromycin from Streptomyces collinus is an antibiotic inhibitor of protein synthesis.
Definition
ChEBI: Mocimycin is a C-glycosyl compound.
References
[1] H. WOLF K. N H Zhner. Kirromycin, an inhibitor of the 30 S ribosomal subunits function[J]. FEBS Letters, 1972, 21 3: Pages 347-350. DOI:
10.1016/0014-5793(72)80199-6[2] H WOLF A P G Chinali. Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1974, 71 12: 4910-4914. DOI:
10.1073/pnas.71.12.4910
