50935-71-2

Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli.

Kirromycin from Streptomyces collinus is an antibiotic inhibitor of protein synthesis.

ChEBI: Mocimycin is a C-glycosyl compound.

Store at -20°C

[1] H. WOLF  K. N  H Z?hner. Kirromycin, an inhibitor of the 30 S ribosomal subunits function[J]. FEBS Letters, 1972, 21 3: Pages 347-350. DOI: 10.1016/0014-5793(72)80199-6
[2] H WOLF  A P  G Chinali. Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1974, 71 12: 4910-4914. DOI: 10.1073/pnas.71.12.4910