Chemical Properties
Yellow crystals. Soluble in ethanol, ether, and toluene
Uses
The commercial mixture
of chlorodinitrobenzenes is used to synthesize other
compounds.
Uses
2-Chloro-1,3-dinitrobenzene can be used as intermediates of dyes and pigments. Also used as solvents in HPLC, NMR.
Uses
2,6-Dinitrochlorobenzene (2-Chloro-1,3-dinitrobenzene) is a thiol-modifying agent.
Hazard
Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. May
cause damage to organs through prolonged or repeated exposure. Very
toxic to aquatic life with long lasting effects.
Synthesis
The synthesis of 2-Chloro-1,3-dinitrobenzene is as follows:
Add 800ml of sulfolane as solvent to a 2L flask, then add 246.5g of 3,5-dinitro-4-chlorobenzoic acid and 168g of sodium bicarbonate,Heat to 195°C to react for 2h. After the reaction is complete, cool to 130°C and distill under reduced pressure.The product 2-Chloro-1,3-dinitrobenzene, 178.4g, was obtained by rectification with a yield of 88.1%.
