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(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Structure
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • CAS No.85416-75-7
  • Chemical Name:(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • CBNumber:CB2264846
  • Molecular Formula:C16H21NO3
  • Formula Weight:275.34
  • MOL File:85416-75-7.mol
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Property
  • Melting point: :132.0 to 136.0 °C
  • Boiling point: :472.7±45.0 °C(Predicted)
  • Density  :1.155±0.06 g/cm3(Predicted)
  • storage temp.  :Sealed in dry,Store in freezer, under -20°C
  • pka :16.02±0.40(Predicted)
  • form  :White to off-white solid.
  • FDA UNII :DPX51KUP08
Safety
  • HazardClass  :IRRITANT
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Price More Price(22)
  • Brand: TCI Chemical
  • Product number: R0182
  • Product name : (R)-(-)-Rolipram
  • Purity: >98.0%(HPLC)
  • Packaging: 10mg
  • Price: $162
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: R0182
  • Product name : (R)-(-)-Rolipram
  • Purity: >98.0%(HPLC)
  • Packaging: 50mg
  • Price: $564
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Tocris
  • Product number: 1349
  • Product name : (R)-(-)-Rolipram
  • Purity: ≥98%(HPLC)
  • Packaging: 10
  • Price: $212
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Tocris
  • Product number: 1349
  • Product name : (R)-(-)-Rolipram
  • Purity: ≥98%(HPLC)
  • Packaging: 50
  • Price: $876
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: TRC
  • Product number: R640043
  • Product name : R-(-)-Rolipram
  • Purity: 
  • Packaging: 5mg
  • Price: $140
  • Updated: 2021/12/16
  • Buy: Buy

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Chemical Properties,Usage,Production

  • Uses R-(-)-Rolipram is a phosphodiesterase IV (PDE4) inhibitor and anti-inflammatory agent with some antidepressant activity. It is the R isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor.
  • Biological Activity More active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ); 2-10-fold more potent than the S-(+) enantiomer ((4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one ). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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85416-75-7, (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONERelated Search:
  • (4R)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • (S)-(+)-ROLIPRAM
  • (R)-(-)-ROLIPRAM
  • (4R)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one
  • Rolipram (R)-(-)-
  • (4R)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
  • (<i>R</i>)-(-)-Rolipram
  • 4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone
  • (R)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
  • CS-1181
  • (R)-ROLIPRAM;(-)-ROLIPRAM
  • 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-
  • (?)-Rolipram
  • 85416-75-7
  • Signalling
  • Cyclic Nucleotide related