Uses
2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η
5-C
5H
5)
2Cl
2], [Ti(η
5-C
5H
4Me)
2Cl
2], [Ti(η
5-C
5H
4SiMe
3)(η
5-C
5H
5)Cl
2], [Ti(η
5-C
5Me
5)Cl
3], SnMe
3Cl and Ga
tBu
3:
- [Ti(η5-C5H5)2(DMP-κO)2]
- [Ti(η5-C5H4Me)2(DMP-κO)2]
- [Ti(η5-C5H4SiMe3)(η5-C5H5)(DMP-κO)2
- [Ti(η5-C5Me5)(DMP-κ2O,O′)3]
- [SnMe3(μ-DMP-κO:κO′)]∞
- [GatBu2(μ-DMP-κO:κO′)]2
General Description
2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.
