Chemical Properties
Clear light pink or yellow-green solution
Uses
Flame-retarding agent for cotton fabrics. May
be used in combination with triethylolamine and
urea (Roxel process) or with triethanolamine and
tris(1-aziridinyl) phosphine oxide.
Uses
Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H
2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl
4.3H
2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.
Definition
A crystalline compound made by the reaction of
phosphine, formaldehyde, and hydrochloric acid.
General Description
Clear slightly viscous,colorless to yellow liquid (20% H2O solution).
Air & Water Reactions
Hygroscopic. Water soluble.
Reactivity Profile
Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.
Health Hazard
ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.
Fire Hazard
Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]
