Description
A pyrrolizidine alkaloid obtained from Heliotropiurn supinurn, the base forms
colourless needles when crystallized from Me2CO. It has [α]
D - 23.8° (EtOH)
and on alkaline hydrolysis furnishes trachelantic acid and supinidine. The latter
has b.p. 158-9°C/1O mm; [α]
D - 9.45° (EtOH) and gives a crystalline picrate,
m.p.142-3°C.
Uses
Supinine is a hepatotoxic alkaloid that is excreted through urine as a metabolic pyrrole.
Definition
ChEBI: Supinine is a member of pyrrolizines.
References
Men'shikov, Gurevich.,]. Gen. Chern., USSR, 19,1382 (1949)
