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HOLO-TRANSFERRIN

HOLO-TRANSFERRIN Structure
HOLO-TRANSFERRIN
  • CAS No.11096-37-0
  • Chemical Name:HOLO-TRANSFERRIN
  • CBNumber:CB2103448
  • Molecular Formula:C16H22N6O4
  • Formula Weight:362.38368
  • MOL File:11096-37-0.mol
HOLO-TRANSFERRIN Property
  • storage temp.  :2-8°C
  • solubility  :H2O: 50 mg/mL
  • form  :powder
  • Water Solubility  :Soluble in water (50 mg/ml).
  • CAS DataBase Reference :11096-37-0
  • EPA Substance Registry System :Transferrin (11096-37-0)
Safety
  • Hazard Codes  :B,Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-37/39
  • WGK Germany  :3
  • F  :21
  • TSCA  :Yes
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
HOLO-TRANSFERRIN Price More Price(46)
  • Brand: Sigma-Aldrich
  • Product number: 178481
  • Product name : Transferrin, Apo-, Low Endotoxin Grade, Human Plasma
  • Purity: 
  • Packaging: 100mg
  • Price: $82.9
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 178481
  • Product name : Transferrin, Apo-, Low Endotoxin Grade, Human Plasma
  • Purity: 
  • Packaging: 1gm
  • Price: $903
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: J61626
  • Product name : Transferrin (Apo), bovine plasma
  • Purity: 98+%
  • Packaging: 100mg
  • Price: $20.4
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: J61046
  • Product name : Transferrin (Holo), bovine plasma, 98+%
  • Purity: 
  • Packaging: 1g
  • Price: $204
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 616397-M
  • Product name : Transferrin, Holo, Human Plasma
  • Purity: 
  • Packaging: 500mg-m
  • Price: $325
  • Updated: 2020/08/18
  • Buy: Buy

HOLO-TRANSFERRIN Chemical Properties,Usage,Production

  • Description Holo-transferrin is the transferrin of the holo iron. It is a kind of iron-binding blood plasmaglycoproteins that is capable of regulating the level of free iron (Fe) in biological fluids. It is responsible for iron transportation in vertebrate serum and donating irons to cells through interaction with the CD71 membrane receptor. Transferrin is crucial for proliferating cells as a growth factor to initiate and maintain the DNA synthesis. It can also act as a cytokine. It is mainly synthesized in liver inside the human body. It is responsible to deliver iron from duodenum and white blood cells macrophages to all the other tissues, and is a key protein to maintain in vivo iron homeostasis. Increased plasma transferrin level is related to diseases such as iron deficiency anemia while decrease plasma transferrin is related to iron overload diseases and protein malnutrition.
  • Pharmaceutical Applications Transferrins are a group of proteins that are abundant in blood and their primary role is to transport Fe3+, as free Fe3+ would be toxic to most organisms. Transferrin consists of a single polypeptide chain independently binding a maximum of two Fe3+ ions. Fe3+ is bound in a hexa-coordinated high-spin complex within the protein. The metal is coordinated by the N atom from the imidazole residue, two deprotonated phenol groups, a carboxylate and a carbonato ligand.
  • Purification Methods This transferrin is purified by affinity chromatography on phenyl-boronate agarose followed by DEAE-Sephacel chromatography. The product is free from haemopexin. [Cook et al. Anal Biochem 149 349 1985, Aisen & Listowsky Ann Rev Biochem 49 357 1980.]
  • References https://en.wikipedia.org/wiki/Transferrin
    http://www.prospecbio.com/Holo_Transferrin_Human_11_121/
HOLO-TRANSFERRIN Preparation Products And Raw materials
Raw materials
Preparation Products
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11096-37-0, HOLO-TRANSFERRINRelated Search:
  • HUMAN TRANSFERRIN
  • HUMAN TRASFERRIN
  • HUMAN SEROTRANSFERRIN
  • HUMAN APO-TRANSFERRIN
  • HUMAN HOLO-TRANSFERRIN
  • HOLO-TRANSFERRIN
  • HOLO-TRANSFERRIN BOVINE
  • HOLO-TRANSFERRIN HUMAN
  • APO-TRANSFERRIN
  • APO-TRANSFERRIN HUMAN
  • APO-TRANSFERRIN HUMAN GAMMA-IRRADIATED*C ELL CULTURE
  • APO-TRANSFERRIN HUMAN PARTIALLY*IRON-SAT URATED
  • TRANSFERRIN, HUMAN, 98%, LOW ENDOTOXIN, PARTIALY SA
  • APO-TRANSFERRIN RABBIT APPROX. 98%
  • APO-TRANSFERRIN SHEEP
  • APO-TRANSFERRIN RAT
  • HOLO-TRANSFERRIN,HUMAN, APPROX. 97% ENDO TOXIN TESTED, CELL CULTURE TESTED
  • APO-TRANSFERRIN, HUMAN, APPROX 97% ENDOT OXIN TESTED, CELL CULTURE TESTED
  • TRANSFERRIN BOVINE HOLO-FORM*IRON-SATURA TED CELL CU
  • APO-TRANSFERRIN DOG
  • APO-TRANSFERRIN, BOVINE, CELL*CULTURE TE STED
  • Transferrin,Horse,~96%
  • Transferrin,Human,~94%
  • APO-TRANSFERRIN (FROM HUMAN SERUM)
  • siderophilin, partially saturated
  • siderophilin,partially saturated
  • APO-TRANSFERRIN,POWDER
  • TRANSFERRIN (HOLO), FROM HUMAN PLASMA, PYROGEN-FREE
  • transferrin (serum)
  • Human transferrin, Siderophilin
  • apo-Transferrin from guinea pig
  • apo-Transferrin from sheep
  • Siderophilin, iron-saturated, Siderophilin
  • apo-Transferrin from rabbit
  • apo-Transferrin from rat
  • Holotransferrins
  • Muscle trophic factor
  • PARTIALLY IRON-LOADED
  • SIDEROPHILIN
  • Transferrin, Apo-, Tissue Culture Grade, Human Plasma
  • Transferrin, Holo, TC Grade, Pyrogen-Free, Human Plasma
  • apo-Transferrin from mouse
  • Transferrin, from Rat
  • apo-Transferrin human,Human transferrin, Siderophilin
  • holo-Transferrin human,Siderophilin, iron-saturated
  • Transferrin human,Siderophilin, partially saturated
  • Transferrin for Cell Culture
  • SIDEROPHILIN, IRON-POOR
  • SIDEROPHILIN, IRON-POOR HUMAN
  • SIDEROPHILIN, IRON-SATURATED
  • SIDEROPHILIN, IRON-SATURATED HUMAN
  • SIDEROPHILIN, PARTIALLY SATURATED HUMAN
  • TRANSFERRIN BOVINE (APO)
  • TRANSFERRIN BOVINE (APO FORM)
  • TRANSFERRIN BOVINE (HOLO FORM)
  • TRANSFERRIN (HUMAN BLOOD)
  • TRANSFERRIN HUMAN (HOLO)
  • TRANSFERRIN (APO)