Uses
2-Hydroxy-2-methylbutyric acid can be used as:
- A complexing agent in a new electrolytic system, applicable in the isotachophoretic lanthanide separation.
- An aldehyde surrogate to prepare pyrrolo[1,2-a]quinoxaline derivatives by reacting with 2-(1H-pyrrol-1-yl)aniline.
- A starting material to synthesize Cr(V) reagent named sodium bis(2-hydroxy-2-methylbutyrato)oxochromate(V) (Aldrich cat. no. ALD00006) applicable in the total synthesis of ()-taxuyunnanine D.
Definition
ChEBI: A branched-chain fatty acid that is 2-methylbutyric acid substituted at C-2 by a hydroxy group.
IC 50
Human Endogenous Metabolite
Purification Methods
Crystallise the acid from *benzene, and sublime it at 90o. [Beilstein 3 H 324.] IRRITANT.
