Chemical Properties
WHITE TO OFF-WHITE POWDER
Uses
Nω-Nitro-L-arginine is an inhibitor for nitric oxide synthase and is used in the study of bacterium to determine effective treatments. Used in the study of MRSA (Methicillin-Resistant Staphylococcus Aureus).
Definition
ChEBI: N(gamma)-nitro-L-arginine is an L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group. It is a L-arginine derivative, a N-nitro compound, a member of guanidines and a non-proteinogenic L-alpha-amino acid.
Hazard
A reproductive hazard.
Biological Activity
NO synthase inhibitor.
Biochem/physiol Actions
Nω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia.
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits toxicvapors of NOx.