Description
Fusarenon X is a type B trichothecene mycotoxin typically derived from
Fusarium species. It is primarily found in contaminated cereals. Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis. As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity. Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.
Safety Profile
Poison by ingestion,
subcutaneous, intravenous, and
intraperitoneal routes. An experimental
teratogen. Experimental reproductive
effects. Questionable carcinogen with
experimental tumorigenic data. Human
mutation data reported. When heated to
decomposition it emits acrid smoke and
irritating fumes.
