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Glycyrrhizic acid ammonium salt

Glycyrrhizic acid ammonium salt Structure
Glycyrrhizic acid ammonium salt
  • CAS No.53956-04-0
  • Chemical Name:Glycyrrhizic acid ammonium salt
  • CBNumber:CB1492372
  • Molecular Formula:C42H65NO16
  • Formula Weight:839.97
  • MOL File:53956-04-0.mol
Glycyrrhizic acid ammonium salt Property
Safety
  • RIDADR  :UN 3077 9 / PGIII
  • WGK Germany  :2
  • RTECS  :LZ6500000
  • F  :3-10
  • HS Code  :29389090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Glycyrrhizic acid ammonium salt Price More Price(17)
  • Brand: Sigma-Aldrich
  • Product number: Y0000433
  • Product name : Ammonium glycyrrhizate
  • Purity: European Pharmacopoeia (EP) Reference Standard
  • Packaging: 
  • Price: $190
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 01250570
  • Product name : Glycyrrhizic acid ammonium salt
  • Purity: primary reference standard
  • Packaging: 50mg
  • Price: $238
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1029929
  • Product name : Ammonium glycyrrhizate
  • Purity: United States Pharmacopeia (USP) Reference Standard
  • Packaging: 100mg
  • Price: $399
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: G0151
  • Product name : Monoammonium Glycyrrhizinate Hydrate
  • Purity: >75.0%(HPLC)
  • Packaging: 1g
  • Price: $17
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: G0151
  • Product name : Monoammonium Glycyrrhizinate Hydrate
  • Purity: >75.0%(HPLC)
  • Packaging: 25g
  • Price: $59
  • Updated: 2021/03/22
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Glycyrrhizic acid ammonium salt Chemical Properties,Usage,Production

  • Description § 184.1408(a)(1) Licorice (glycyrrhiza) root is the dried and ground rhizome and root portions of Glycyrrhiza glabra or other species of glycyrrhiza. Licorice extract is that portion of the licorice root that is, after maceration, extracted by boiling water. The extract can be further purified by filtration and by treatment with acids and ethyl alcohol. Licorice extract is sold as a liquid paste ("block"), or spraydried powder. (2) Ammoniated glycyrrhizin is prepared from the water extract of licorice root by acid precipitation followed by neutralization with dilute ammonia. Monoammonium glycyrrhizinate (C42H61016NH45H2O ) is prepared from ammoniated glycyrrhizin by solvent extraction and separation techniques.
  • Chemical Properties Licorice (glycyrrhiza) root is the dried and ground rhizome and root portions of Glycyrrhiza glabra or other species of glycyrrhiza Ammoniated glycyrrhizin is prepared from the water extract of licorice root by acid precipitation, followed by neutral- ization with dilute ammonia Monoammonium glycyrrhizinate (C42H62O16NH45H2O) is prepared from ammoniated glycyrrhizin by solvent extraction and separation techniques.
  • Chemical Properties white to slightly yellow powder
  • Uses Ammonium Glycyrrhizinate is used in the synthesis of polyion complex nanocarriers which may act as a template for the design of other negatively charged water-soluble drugs. Particularly for anti-infl ammatory drugs with which Ammonium Glycyrrhizinate is associated.
  • Uses anti-cancer agent
  • Uses pharmaceutical excipient, GRAS, sweetener
  • Uses Glycyrrhizic acid ammonium salt is a flavoring and sweetening agent obtained from licorice flavonoids. It has a slight licorice flavor and an intense and rounded sweetness. It is soluble in water, glycerin, and propylene glycol and has good thermal stability but can degrade under prolonged heating. It is stable over a ph of 3.5–9 but could precipitate below ph of 3.5. It can be used in beverages, desserts, confectionary products, soups, and dressings.
  • Anticancer Research Glycyrrhizin (GL) is a saponin-like compound that provides the main sweet flavourfor G. glabra (licorice), and it is commonly used in clinical treatment for itsoutstanding pharmacological action such as antitumour, anti-inflammatory andanti-oxidativeactions (Rebhun et al. 2015; Wu et al. 2015). Cai et al. (2017) triedto evaluate the anticancer properties of GA and GL against TNBC in combinationwith etoposide.
  • Safety Profile Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NH3.
  • Purification Methods Crystallise the ammonium salt from glacial acetic acid, then dissolve it in ethanolic ammonia and evaporate. The pentahydrate forms needles from 75% aqueous EtOH, m 212-217o. The free acid crystallises from glacial acetic acid. [Karrer et al. Helv Chim Acta 4 100 1921, Lithgoe & Tripett J Chem Soc 1983, 1987 1950, Beilstein 18 IV 5156.]
Glycyrrhizic acid ammonium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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53956-04-0, Glycyrrhizic acid ammonium saltRelated Search:
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  • AMMONIUM 10-[6-CARBOXY-3-(6-CARBOXY-3,4,5-TRIHYDROXY-OXAN-2-YL)OXY-4,5-DIHYDROXY-OXAN-2-YL]OXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-3,4,5,6,6A,7,8,8A,10,11,12,14B-DODECAHYDRO-1H-PICENE-2-CARBOXYLATE
  • AMMONIATED GLYCYRRHIZIN
  • 3-O-(2-O-BETA-D-GLUCOPYRANURONOSYL-ALPHA-D-GLUCOPYRANURONOSYL)-18BETA-GLYCYRRHETINIC ACID AMMONIUM SALT
  • GLYCAMIL
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  • GLYCYRRHIZINATE MONOAMMONIUM SALT
  • Glycyrrhizic acid monoammonium salt trihydrate,98%
  • GLYCYRRHIZIC ACID, AMMONIUM SALT(RG)
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  • aMMoniuM (2S,3S,4S,5R,6S)-5-((2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yloxy)-6-((3S,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptaMethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydrop
  • Glycyrrhizic Acid Monoammonium Salt Glycyrrhizin Monoammonium Salt
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  • Monoammonium glycyrrhizinate Glycyrrhizic acid ammonium
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  • Glycyrrhizic acid ammonium salt 53956-04-0
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  • .alpha.-D-Glucopyranosiduronicacid,(3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl2-O-.beta.-D-glucopyranuronosyl-,monoammoniumsalt
  • ammoniate
  • Ammoniumglycynhizinato
  • ammoniumglycyrrhizate
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  • GLYCYRRHIZINICACIDAMMONIUMSALT
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  • AMMONIUMGLYCYRRHIZIN
  • AMMONIATEDGLYCERRHIZIN
  • (2S,3S,4S,5R,6S)-6-[[(3S,4aS,6aR,6bS,8aR,11S,12aR,14aS,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-5-[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxy-oxan-2-yl]oxy-3,4-dihydroxy-oxane-2-carboxylic acid
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