Uses
L-alpha-Phosphatidyl-L-serine Sodium Salt is a useful research chemical, and has been used in the development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice.
Description
DSPS, 1,2-Distearoyl-sn-glycero-3-phospho-L-serine, is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
Uses
18:0 PS has been used to evaluate its affinity to cytochrome c using surface plasmon resonance (SPR) technique and in the preparation of phospholipid vesicles. It may be used in the preparation of polydimethylsiloxane (PDMS) hybrid microbubbles.
General Description
Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.
Biochem/physiol Actions
Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.
