Chemical Properties
White to light beige crystalline powder
Uses
Reactant for:
- Preparation of acitretin analogs with antitumor activity
- Stereoselective synthesis of essential building blocks of phorboxazole A via hetero Diels-Alder and stereoselective hetero-Michael addition/equilibration
- Preparation of C1-C14 fragment of sarcoglaucol-16-one via Z-selective ando-type Horner-Wadsworth-Emmons olefination
- Wittig reactions
- Synthesis of ring-expanded and epothilone-hybridized macrosphelide analogs as apoptosis-inducing agents
- Preparation of phosphonic acid-containing analogs of mycophenolic acid as inhibitors of IMPDH
Uses
Reactant for:• ;Preparation of acitretin analogs with antitumor activity1• ;Stereoselective synthesis of essential building blocks of phorboxazole A via hetero Diels-Alder and stereoselective hetero-Michael addition/equilibration2• ;Preparation of C1-C14 fragment of sarcoglaucol-16-one via Z-selective ando-type Horner-Wadsworth-Emmons olefination3• ;Wittig reactions4• ;Synthesis of ring-expanded and epothilone-hybridized macrosphelide analogs as apoptosis-inducing agents5• ;Preparation of phosphonic acid-containing analogs of mycophenolic acid as inhibitors
Uses
2-(Triphenylphosphoranylidene)propionaldehyde is a reagent used in the asymmetric synthesis of hispidanin A via oxidative alkoxylation and stereoselective Diels-Alder reaction. Also acts as a reagent in the stereoselective synthesis of 10-epi-tirandamycin E.