Chemical Properties
off-white to light yellow or beige crystals,
Uses
pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives; the nitrate esters find use as vasodilators and coronary disease therapeutics.
Uses
D-Isosorbide is used as a reagent in the preparation of detergents, agrochemicals, cleansers, cosmetics and vasodilators. It is also employed as a pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives, which is used as vasodilators and coronary disease therapeutics. It is used in the treatment of hydrocephalus and glaucoma. It finds application as a building block for polymers like polycarbonates and polyesters.
Uses
Isosorbide is a reagent widely used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.
Definition
A polyol with a hydroxyl group attached to each of
two cis-oriented saturated furan rings. Intermediate
for pharmaceuticals. Combustible.
brand name
Ismotic (Alcon).
Biological Functions
emergency treatment of acute angle-closure glaucoma.
It should not be confused with isosorbide dinitrate, an
antianginal drug.
Flammability and Explosibility
Non flammable
Clinical Use
Isosorbide is basically a bicyclic form of sorbitol that is used orally to cause a reduction in intraocular pressure in glaucoma cases. Although a diuretic effect is noted, its
ophthalmologic properties are its primary value.
