Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the root or bark of Schisandra chinensis.
Uses
Anwuligan has anti-tumor and coagulation effects.
Definition
ChEBI: 4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol is a lignan.
Biological Activity
Macelignan is a neuroprotective lingan isolated from nutmeg (Myristica fragrans) th at protects dopaminergic neurons from inflammatory degeneration. Apparently, the neuroprotective effect of macelignan is mediated by PPARγ activation and arginase-1 expression. Macelignan inhibits LPS induced production of NO as well and inflammatory cytokines including TNF and IL- 1β in primary cultures of microglia.
target
PAFR | Antifection
