Description
Several different arachidonoyl amino acids, including N-
arachidonoyl dopamine (NADA) and N-
arachidonoyl serine (ARA-
S), have been isolated and characterized from bovine brain. During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered. This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels. N-
Stearoyl taurine is a prominent amino-
acyl endocannabinoid isolated from rat brain during lipidomics profiling.