Chemical Properties
White to off-white powder
Uses
Sodium taurocholate is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Uses
selectively activates retinoid X receptors (RXRs)
Definition
ChEBI: Sodium taurocholate is a bile salt. It contains a taurocholate.
Biological Activity
Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.
Purification Methods
Purify it by recrystallisation and gel chromatography using Sephadex LH-20. [Beilstein 10 III 1655, 10 IV 2078.]