2[(1-Oxooctadecyl)amino]-ethanesulfonic acid

Product Name2[(1-Oxooctadecyl)amino]-ethanesulfonic acid
CAS63155-80-6
MFC20H41NO4S
MW391.61
EINECS
MOL File63155-80-6.mol

Chemical Properties

Melting point	240 °C (approx, decomp)
Density	1.022±0.06 g/cm3(Predicted)
solubility	DMF: 1.5 mg/ml; DMSO: 1.5 mg/ml
form	Liquid
pka	1.42±0.50(Predicted)
color	Colorless to light yellow

Usage And Synthesis

Description

Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain. During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered. This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels. N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling.

Uses

N-Stearoyl Taurine is a prominent amino-acyl endocannabinoid.

Definition

ChEBI: N-stearoyltaurine is a fatty acid-taurine conjugate derived from stearic acid. It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid. It is a conjugate acid of a N-stearoyltaurine(1-).

References

[1] SUNDERLAND D, UZOIGWE G N. Personal Communication[J]. Communications in Africa, 1880–1939, 2018, 73 1: 0. DOI: 10.4324/9781351112277-85
[2] ALAN SAGHATELIAN. A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels[J]. Biochemistry Biochemistry, 2006, 45 30: 9007-9015. DOI: 10.1021/bi0608008