Chemical Properties
colorless to beige crystalline flakes
Uses
Perillic Acid is an apoptosis inducing agent via an increase in p21, Bax, and caspase-3 in cells.A possible biomarker of Parkinson’s disease.
General Description
(
S)-(-)-Perillic acid is a perillyl derivative with potent antimicrobial and anticancer activity. It can be prepared via bio-oxidation of
R-(+)-limonene.
Biochem/physiol Actions
Interferes with activity of p21ras and other small G proteins by inhibiting post-translational cysteine isoprenylation.
