2-[(1S,3S)-3-hydroxycyclohexyl]-5-(2-methyloctan-2-yl)phenol

Description

(±)-epi CP 47,497 is an analytical reference standard that is structurally categorized as a cannabinoid (CB). It is an epimer of (±)-CP 47,497 . (±)-CP 47,497 is a synthetic cannabinoid that avidly binds the CB₁ receptor (K_i = 2.2 nM) and is equivalent in analgesic potency to Δ⁹-THC.^1,2 (±)-epi CP 47,497 is regulated as a Schedule 1 drug in the United States. This product is intended for research and forensic applications.

References

[1] Huffman, J.W., Thompson, A.L.S., Wiley, J.L., et al. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940 Bioorg. Med. Chem. 16(1),322-335(2008).
[2] Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs Mol. Pharmacol. 44(5),1008-1015(1993).