Chemical Properties
WHITE FINE CRYSTALS OR CRYSTALLINE POWDER
Uses
4-tert-Butylcyclohexanecarboxylic Acid has been used as a reactant in the synthesis of cycloalkylamide derivatives as inhibitors of soluble epoxide hydrolase.
Uses
4-
tert-Butylcyclohexanecarboxylic acid may be used in the preparation of
N-((
S)-3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)-1-henylpropyl)-4-
tert-butylcyclohexanecarboxamide.
Definition
ChEBI: Trans-4-tert-butylcyclohexanecarboxylic acid is a monocarboxylic acid that is cyclohexanecarboxylic acid substituted by a tert-butyl group at position 4 (the trans-stereoisomer). It has a role as a metabolite. It derives from a hydride of a cyclohexane.
General Description
delta pKa between the two stereoisomers of 4-tert-butylcyclohexanecarboxylic acid has been studied using 1H and 13C NMR. Preparation of
cis- and
trans-4-
tert- butylcyclohexanecarboxylic acid has been reported.
