Description
One of three closely related alkaloid isolated from Securinega suffructicosa, the base has [α]
17D + 58.2° (c 0.14, CHC1
3) or + 50° (dioxan). It yields a crystalline picrate, m.p. l86-7°C (dec.), and a 3: 5-dinitrobenzoate, m.p. 198-9°C;[α]
17D + 55.3° (c 0.10, CHC1
3). On hydrogenation with Pt0
2 in AcOH it gives the dihydro derivative, forming a hydrochloride, m.p. 241- 2°C. When treated with methylsulphonyl chloride in pyridine, the base furnishes viroallosecurinine, m.p. 133- 4°C; [α]
D + 1200° (c 0.01, EtOH).
References
Horii et al., Chern. Pharrn. Bull., 13, 1307 (1965)
