Chemical Properties
Off-White Solid
Uses
Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells.
Uses
1,2-Dioctanoyl-sn-glycerol is a cell permeable analog of the PKC-activating second messenger DAG. 1,2-Dioctanoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.[Cayman Chemical]
Definition
ChEBI: 1,2-diacyl-sn-glycerol in which both the 1- and 2-acyl groups are specified as octanoyl.
Biological Activity
Cell permeable: yes', 'Primary Target
Protein kinase C', 'Reversible: no
