Chemical Properties
CLEAR SLIGHTLY YELLOW LIQUID
Uses
Additive for light and heat stability of polyamide 6 containing hindered piperidine amines and tertiary amines
Template for preparation of ammoniopiperidinium hydrogen phosphates
Fiber-reactive yellowing inhibitor for partial brightness stabilization of peroxide-bleached pulps
Reactant for thermostability of soybean / sunflower oils
Uses
Triacetonediamine have been investigated as new anticancer drugs with high activity and low toxicity.
Preparation
Triacetonediamine is formed by the poly-aldol condensation of acetone in the presence of ammonia and calcium chloride:
3 (CH3)2CO + NH3 → OC(CH2CMe2)2NH + 2 H2O
Reactions
Triacetonediamine is an intermediate in the preparation of 2,2,6,6-tetramethylpiperidine, a sterically hindered base and precursor to the reagent called TEMPO. Reductive amination of triacetonamine gives 4-amino-2,2,6,6-tetramethylpiperidine.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors ofNOx.
